Hm… Diaspora: Shattered Armistice ( #BSG ) didn’t want to start any more. Found only this in the launcher:

The executable did not generate a flag file

Turned out my install was missing some 32bit lib:

ldd /home/beko/.local/share/lutris/runners/wine/lutris-ge-6.16-1-x86_64/lib/wine/i386-unix/openal32.dll.so
linux-gate.so.1 (0xf7eca000)
libopenal.so.1 => not found
libc.so.6 => /lib/libc.so.6 (0xf7c8f000)
/lib/ld-linux.so.2 (0xf7ecc000)

A dnf install wine-openal.i686 fixed this for me.

Yes, I know there is a native Linux PC version but it’s a pain in the neck to compile 🤷